Tuesday, November 18, 2014

Causes of Vitamin B12 deficiency -Long-term use of pantoprazole ,omeprazole

Causes of Vitamin B12 Deficiency
Vitamin B12 deficiency can happen if you have certain conditions, such as:
  • Atrophic gastritis, in which your stomach lining has thinned 
  • Pernicious anemia, which makes it hard for your body to absorb vitamin B12
  • Surgery that removed part of your stomach or small intestine, including weight loss surgery
  • Conditions affecting the small intestine, such as Crohn's disease,celiac disease, bacterial growth, or a parasite
  • Heavy drinking
  • Immune system disorders, such as Graves' disease or lupus
  • Long-term use of acid-reducing drugs ,pantoprazole ,omeprazole, lansoprazole ,rabeprazol . 
  • -The diabetes medication metformin may interfere with B12 dietary absorption
  •  pantoprazole may lead to a reduced absorption of vitamin B12.

  • Doctor Advice -You can also get vitamin B12 deficiency if you're a vegan (meaning you don't eat any animal products, including meat, milk, cheese, and eggs) or a vegetarian who doesn't eat enough eggs or dairy products to meet your vitamin B12 needs.

  • Babies born to mothers who are vegetarians may also not get enough vitamin B12.

Vitamin B12 is vital for the formation of red blood cells, as well as for the proper functioning and health of nerve tissue. If left untreated, vitamin B12 deficiency, also known as B12deficiency, can lead to anemia, as well as nerve and brain damage, which may eventually become irreversible.
a symptom is headache, while a skin rash or swelling are examples of signs.
This production goes down if your vitamin B12 levels are deficient, resulting in anemia as the red blood cell count drops.
The most common symptoms of anemia are:
  • Fatigue (tiredness)
  • Panting (shortness of breath)
  • Palpitations (disagreeable sensations of irregular or heavy beating of the heart).

B12 deficiency anemia may also be caused by a lack of intrinsic factor - pernicious anemia. The patient's digestive system cannot absorb B12 properly.
Anemia may also have the following signs and symptoms:
  • A sore mouth or tongue
  • Weight loss
  • Pale or yellowish skin
  • Diarrhea (sporadic)
  • Menstrual problems
  • Higher susceptibility to infections.
If the deficiency continues untreated the patient may have the following neurological signs and symptoms:
  • Tingling or numbness of the fingers
  • Tingling or numbness of the toes
  • General muscle weakness
  • Difficulty walking properly (staggering)
  • Irritability
  • Confusion
  • Forgetfulness
  • Tender calves.

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